Cơ chế kết tập và kết dính tiểu cầu:

xuất huyết giảm TC do giảm chất lượng TC:

Giảm khả năng kết dính( adhesion)
Bernard–Soulier syndrome (BSS), also called hemorrhagiparous thrombocytic dystrophy,[1] is a rare autosomal recessive coagulopathy (bleeding disorder) that causes a deficiency of glycoprotein Ib (GpIb), the receptor for von Willebrand factor, which is important in clot formation.

Giảm khả năng kết tập( aggregation)
Glanzmann's thrombasthenia is an abnormality of the platelets.[1] It is an extremely rare coagulopathy (disorder of the blood), in which the platelets lack glycoprotein IIb/IIIa. Hence, no fibrinogen bridging can occur, and bleeding time is significantly prolonged.