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robbenisme
22-01-11, 06:06 AM
Synergism: defined as inhibition of growth by the drug combination at concentrations less than or equal to 25% of the MIC of each drug acting alone.
Additive: 50% of the inhibitory concentration of each drug is required to produced inhibition.
Antagonistic: more than 50% of the MIC of each drug is necessary to produce an inhibitory effect.
Tham khảo: Goodman and Gillman's - manual of pharmacology and therapeutics.